Though this song is perhaps best known from HBO's Treme (Season 1, Episode 4; see that version here), the rendition below may be, to quote from a comment on its YouTube page, the "Best. Version. Ever."
According to a Threadhead Records post, Boutte and Sanchez "met at a backyard party thrown by musician Michelle Shocked, whom Sanchez met during his time in New York City. They developed a friendship that led to mutual admiration when they realized the eerie similarities in their lives. Their birthdays are one day apart, their sisters raised them both and their fathers were buried in the same cemetery at the end of Canal Street."
This is one of a number of excellent videos by James DeMaria; check out his YouTube channel here.
Paul, John, and a rubber chicken, at 'OZ, during the Spring 2009 Membership Drive: